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Table 5 Hazard ratios (HR) of parkinsonism by number of prescriptions of disulfiram

From: Exposure to disulfiram and incidence of parkinsonism

 

N parkinsonism cases

Person-years

Model 1a

Model 2b

HR

95% CI

HR

95% CI

Number of disulfiram prescriptions

 Unexposed

19,064

15,020,303

1

 

1

 

 2–4 prescriptions

4

3,285.21

2.486

0.928–6.658

1.553

0.579–4.166

 > 4 prescriptions

4

2,096.60

4.128

1.561–10.916

2.958

1.109–7.893

 Trend test (p-value)

  

< 0.001

0.022

  1. a adjusted for sex (strata), age and age squared
  2. b adjusted for sex (strata), age, age squared and antipsychotic exposure
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Journal of Occupational Medicine and Toxicology

ISSN: 1745-6673