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Table 4 Hazard ratios (HR) of parkinsonism by exposure to disulfiram therapy, stratified by exposure to neuroleptics

From: Exposure to disulfiram and incidence of parkinsonism

 

Ever exposed to Neuroleptics

Never exposed to Neuroleptics

N parkinsonism cases

Person-years

HRa

95% CI

N parkinsonism cases

Person-years

HRa

95% CI

Disulfiram

Unexposed

2,423

573,126

1

 

16,641

14,447,177

1

 

Exposed

2

1,693

0.644

0.160–2.586

6

3,981

3.422

1.537–7.621

Total

 

2,425

574,819

  

16,647

14,450,866

  
  1. a adjusted for sex (strata), age and age squared
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Journal of Occupational Medicine and Toxicology

ISSN: 1745-6673