Exposure to disulfiram and incidence of parkinsonism

Table 3 Hazard ratios (HR) of parkinsonism by exposure to disulfiram postponed 1-year after the first prescription and neuroleptics therapy

		N parkinsonism cases	Person-years	Model 1^a		Model 2^b
		N parkinsonism cases	Person-years	HR	95% CI	HR	95% CI
Disulfiram (lagged 1 year from the first prescription)	Unexposed	19,066	15,021,186	1		1
Disulfiram (lagged 1 year from the first prescription)	Exposed	6	4,499	2.702	1.215–6.010	1.751	0.784–3.910
Neuroleptics	Unexposed	16,665	14,670,915			1
Neuroleptics	Exposed	2,407	354,770			4.170	3.986–4.364

ISSN: 1745-6673