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Table 4 Average Ashcroft scores by sex and group of the mean and median Ashcroft scores per animal

From: Pathological characterization of lung fibrosis in Sprague–Dawley rats treated with fluoro-edenite fibres by intrapleural injection

Group

Treatment

Dose

(mg/cc H2O)

Route of administration

Animals

Ashcroft scores

Mean

Ashcroft scores

Median

Sex

No

Mean

SD

Mean

SD

I

Fibrous FE

25

Intrapleural Injection

M

F

40

40

1.58*

2.28*

0.87

0.95

1.05*

1.95*

1.22

1.59

II

-

0

Injection with water

M

39

0.47

0.24

0.01

0.08

  

(control)

 

F

39

0.60

0.20

0.01

0.08

  1. *Statistically significant with Mann–Whitney test (P < 0.0001)
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Journal of Occupational Medicine and Toxicology

ISSN: 1745-6673