Table 3 Predictors for severe PCS overall, as well as for the three most frequent severe symptoms

Sex (ref: men)

OR 1.78

(1.29–2.45; p < 0.001)

OR 1.64

(1.09–2.49; p = 0.019)

OR 1.73

(0.99–3.05; p = 0.056)

OR 2.10

(1.06–4.17; p = 0.034)

Age in years

OR 1.00

(0.99–1.01; p = 0.950)

OR 1.00

(0.99–1.02; p = 0.597)

OR 0.99

(0.97-1.00; p = 0.098)

OR 1.01

(0.99–1.02; p = 0.526)

Cardiovascular diseases

OR 1.35

(1.04–1.77; p = 0.025)

-

-

-

Respiratory diseases

OR 1.94

(1.44–2.61; p < 0.001)

OR 1.68

(1.17–2.42; p = 0.005)

OR 1.63

(1.03–2.58; p = 0.039)

OR 4.21

(2.71–6.54; p < 0.001)

Mental disorders

OR 1.36

(0.99–1.85; p = 0.053)

OR 1.93

(1.35–2.76; p < 0.001)

OR 2.53

(1.64–3.89; p < 0.001)

OR 1.67

(1.01–2.78; p = 0.047)

Urogenital diseases

OR 1.79

(1.10–2.91; p = 0.018)

OR 1.87

(1.07–3.28; p = 0.029)

-

-

BMI (ref.: normal weight)

-

-

-

-

Underweight

OR 3.30

(1.56–6.99; p = 0.002)

OR 3.95

(1.72–9.08; p = 0.001)

OR 2.55

(0.82–7.90; p = 0.104)

OR 4.95

(1.53–16.05; p = 0.008)

Overweight

OR 1.38

(1.06–1.81; p = 0.017)

OR 1.47

(1.04–2.07; p = 0.029)

OR 1.19

(0.75–1.90; p = 0.461)

OR 1.84

(1.04–3.26; p = 0.036)

Obesity

OR 1.56

(1.16–2.09; p = 0.003)

OR 1.72

(1.20–2.46; p = 0.003)

OR 1.79

(1.12–2.88; p = 0.016)

OR 2.76

(1.58–4.83; p < 0.001)

Physical exercise (ref: no exercise)

-

-

-

-

1 h/week

-

-

OR 1.32

(0.81–2.16; p = 0.266)

-

2–3 h/week

-

-

OR 1.76

(1.11–2.82; p = 0.017)

-

> 3 h/week

-

-

OR 0.95

(0.50–1.83; p = 0.888)

-

Smoking

OR 1.46

(1.10–1.95; p = 0.008)

OR 1.53

(1.07–2.18; p = 0.019)

OR 1.69

(1.09–2.63; p = 0.019)

-

Hospitalisation (ref: no hospitalisation)

-

-

-

-

Inpatient

OR 1.93

(1.24–3.02; p = 0.004)

OR 2.22

(1.32–3.71; p = 0.002)

OR 2.40

(1.28–4.50; p = 0.007)

OR 2.58

(1.35–4.93; p = 0.004)

ICU

OR 4.26

(2.10–8.63; p < 0.001)

OR 4.29

(2.03–9.05; p < 0.001)

OR 2.28

(0.81–6.43; p = 0.121)

OR 3.22

(1.18–8.80; p = 0.022)